Partition coefficients

Source: R/params.R

Partition coefficients for commonly used volatile anaesthetics.

partition_coefficients(
  anaesthetic = c("nitrous-oxide", "diethyl-ether", "halothane")
)

Arguments

anaesthetic

character(1), anaesthetic

Value

a named numeric with partition coefficients for lung, vrg (vessel rich group, visceral: brain, heart, kidney, ...), mus (muscle, lean tissue: muscle, skin, subcutaneous tissue, ...), and fat (fat, fatty tissue: yellow marrow, fat) for the given anaesthetic.

References

Table 2 in Cowles, A. L., Borgstedt, H. H., & Gillies, A. J. (1973). A simplified digital method for predicting anesthetic uptake and distribution. Computers in Biology and Medicine, 3(4), 385-395. doi:10.1016/0010-4825(73)90004-8

Examples

partition_coefficients("nitrous-oxide")
#>  lung   vrg   mus   fat 
#> 0.463 0.463 0.463 1.030