Chronisch Lymphatische Leukämie Guidline and Quality indicator
0.2.0 - ci-build
Chronisch Lymphatische Leukämie Guidline and Quality indicator - Local Development build (v0.2.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
Active as of 2025-01-16 |
{
"resourceType" : "EvidenceVariable",
"id" : "PopulationCLLBinetAB",
"meta" : {
"profile" : [
🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria"
]
},
"text" : {
"status" : "generated",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: EvidenceVariable PopulationCLLBinetAB</b></p><a name=\"PopulationCLLBinetAB\"> </a><a name=\"hcPopulationCLLBinetAB\"> </a><a name=\"PopulationCLLBinetAB-en-US\"> </a><p><b>url</b>: <a href=\"EvidenceVariable-PopulationCLLBinetAB.html\">EvidenceVariable Population: CLL und Binet Stadium AB </a></p><p><b>name</b>: PopulationCLLBinetAB</p><p><b>title</b>: Population: CLL und Binet Stadium AB </p><p><b>status</b>: Active</p><p><b>date</b>: 2025-01-16 09:02:23+0000</p><p><b>description</b>: </p><div><p>Population, bei der Binet A oder B sowie eine bestimmte klinische Symptomatik vorliegt</p>\n</div><p><b>actual</b>: false</p><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 92814006}\">Chronic lymphoid leukaemia, disease</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: Any of</p><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 1149099005}\">Binet staging classification for chronic lymphocytic leukemia</span></td><td><span title=\"Codes:{http://snomed.info/sct 863741000000108}\">Clinical stage A chronic lymphocytic leukaemia</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 1149099005}\">Binet staging classification for chronic lymphocytic leukemia</span></td><td><span title=\"Codes:{http://snomed.info/sct 863761000000109}\">Clinical stage B chronic lymphocytic leukaemia</span></td></tr></table></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: Any of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 161832001}\">Weight decreasing</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 7520000}\">Pyrexia of unknown origin</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 42984000}\">Night sweats</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 271737000}\">Anemia</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 718-7}\">Hemoglobin [Mass/volume] in Blood</span></td><td><span title=\"Codes:{http://snomed.info/sct 260371004}\">Decreasing</span></td></tr></table></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 302215000}\">Thrombocytopenic disorder</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 26515-7}\">Platelets [#/volume] in Blood</span></td><td><span title=\"Codes:{http://snomed.info/sct 260371004}\">Decreasing</span></td></tr></table></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2 porecotr}\">Poor response to corticosteroid treatment</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: Any of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 413603009}\">Autoimmune hemolytic anemia</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 2897005}\">Immune thrombocytopenia</span></td></tr></table></blockquote></blockquote></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2 sycasp}\">Symptom-causing splenomegaly</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 246120007}\">Nodule size</span></td><td>10-?</td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 30746006}\">Lymphadenopathy</span></td></tr></table></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 246120007}\">Nodule size</span></td><td><span title=\"Codes:{http://snomed.info/sct 260369004}\">Increasing</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 404684003}\">Clinical finding (finding)</span></td><td><span title=\"Codes:{http://snomed.info/sct 30746006}\">Lymphadenopathy</span></td></tr></table></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 26474-7}\">Lymphocytes [#/volume] in Blood</span></td><td><span title=\"Codes:{https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2 ingrfiftyintwomo}\">Zunahme mehr als 50 Prozent innerhalb von 2 Monaten, gemessen ab einer absoluten Lymphozytenzahl von mindestens 30.000/µl</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 26474-7}\">Lymphocytes [#/volume] in Blood</span></td><td><span title=\"Codes:{https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2 dopeunsixmo}\">Lymphozytenverdopplungszeit unter 6 Monaten, gemessen ab einer absoluten Lymphozytenzahl von mindestens 30.000/µl</span></td></tr></table></blockquote></blockquote></blockquote></blockquote></blockquote></div>"
},
"url" : "https://www.medizin.uni-greifswald.de/fhir/guideline/cll/EvidenceVariable/PopulationCLLBinetAB",
"name" : "PopulationCLLBinetAB",
"title" : "Population: CLL und Binet Stadium AB ",
"status" : "active",
"date" : "2025-01-16T09:02:23+00:00",
"description" : "Population, bei der Binet A oder B sowie eine bestimmte klinische Symptomatik vorliegt",
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"characteristic" : [
{
"definitionByCombination" : {
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{
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"display" : "Clinical finding (finding)"
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{
"definitionByCombination" : {
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{
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{
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},
"valueCodeableConcept" : {
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{
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"display" : "Pyrexia of unknown origin"
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{
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{
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{
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{
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}
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},
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{
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"code" : "271737000",
"display" : "Anemia"
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}
},
{
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"definitionByTypeAndValue" : {
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{
"system" : "http://loinc.org",
"code" : "718-7",
"display" : "Hemoglobin [Mass/volume] in Blood"
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{
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{
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{
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}
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},
"valueCodeableConcept" : {
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{
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"code" : "302215000",
"display" : "Thrombocytopenic disorder"
}
]
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}
},
{
"linkId" : "CLL",
"definitionByTypeAndValue" : {
"type" : {
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{
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"code" : "26515-7",
"display" : "Platelets [#/volume] in Blood"
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{
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{
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{
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"coding" : [
{
"system" : "https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2",
"code" : "porecotr",
"display" : "Poor response to corticosteroid treatment"
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]
}
}
},
{
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"characteristic" : [
{
"linkId" : "CLL",
"definitionByTypeAndValue" : {
"type" : {
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"display" : "Clinical finding (finding)"
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},
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{
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"display" : "Autoimmune hemolytic anemia"
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}
},
{
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"definitionByTypeAndValue" : {
"type" : {
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{
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}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "http://snomed.info/sct",
"code" : "2897005",
"display" : "Immune thrombocytopenia"
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}
}
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}
]
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},
{
"linkId" : "CLL",
"definitionByTypeAndValue" : {
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{
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{
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"code" : "sycasp",
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{
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{
"linkId" : "CLL",
"definitionByTypeAndValue" : {
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{
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"display" : "Nodule size"
}
]
},
"valueRange" : {
"low" : {
"value" : 10,
"system" : "http://unitsofmeasure.org",
"code" : "cm"
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},
{
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{
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{
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{
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{
"linkId" : "CLL",
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{
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]
},
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{
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},
{
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{
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},
{
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{
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"display" : "Lymphocytes [#/volume] in Blood"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2",
"code" : "ingrfiftyintwomo",
"display" : "Zunahme mehr als 50 Prozent innerhalb von 2 Monaten, gemessen ab einer absoluten Lymphozytenzahl von mindestens 30.000/µl"
}
]
}
}
},
{
"linkId" : "CLL",
"definitionByTypeAndValue" : {
"type" : {
"coding" : [
{
"system" : "http://loinc.org",
"code" : "26474-7",
"display" : "Lymphocytes [#/volume] in Blood"
}
]
},
"valueCodeableConcept" : {
"coding" : [
{
"system" : "https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2",
"code" : "dopeunsixmo",
"display" : "Lymphozytenverdopplungszeit unter 6 Monaten, gemessen ab einer absoluten Lymphozytenzahl von mindestens 30.000/µl"
}
]
}
}
}
]
}
}
]
}
}
]
}