DE.UNI-GREIFSWALD.MEDIZIN.CLL-GUIDELINE\Population: CLL und Binet Stadium AB - XML Representation

Chronisch Lymphatische Leukämie Guidline and Quality indicator - Local Development build (v0.2.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
: Population: CLL und Binet Stadium AB - XML Representation

Active as of 2025-01-16
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<EvidenceVariable xmlns="http://hl7.org/fhir">
  <id value="PopulationCLLBinetAB"/>
  <meta>
    <profile
             value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: EvidenceVariable PopulationCLLBinetAB</b></p><a name="PopulationCLLBinetAB"> </a><a name="hcPopulationCLLBinetAB"> </a><a name="PopulationCLLBinetAB-en-US"> </a><p><b>url</b>: <a href="EvidenceVariable-PopulationCLLBinetAB.html">EvidenceVariable Population: CLL und Binet Stadium AB </a></p><p><b>name</b>: PopulationCLLBinetAB</p><p><b>title</b>: Population: CLL und Binet Stadium AB </p><p><b>status</b>: Active</p><p><b>date</b>: 2025-01-16 09:02:23+0000</p><p><b>description</b>: </p><div><p>Population, bei der Binet A oder B sowie eine bestimmte klinische Symptomatik vorliegt</p>
</div><p><b>actual</b>: false</p><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{http://snomed.info/sct 92814006}">Chronic lymphoid leukaemia, disease</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: Any of</p><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 1149099005}">Binet staging classification for chronic lymphocytic leukemia</span></td><td><span title="Codes:{http://snomed.info/sct 863741000000108}">Clinical stage A chronic lymphocytic leukaemia</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 1149099005}">Binet staging classification for chronic lymphocytic leukemia</span></td><td><span title="Codes:{http://snomed.info/sct 863761000000109}">Clinical stage B chronic lymphocytic leukaemia</span></td></tr></table></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: Any of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{http://snomed.info/sct 161832001}">Weight decreasing</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{http://snomed.info/sct 7520000}">Pyrexia of unknown origin</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{http://snomed.info/sct 42984000}">Night sweats</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{http://snomed.info/sct 271737000}">Anemia</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 718-7}">Hemoglobin [Mass/volume] in Blood</span></td><td><span title="Codes:{http://snomed.info/sct 260371004}">Decreasing</span></td></tr></table></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{http://snomed.info/sct 302215000}">Thrombocytopenic disorder</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 26515-7}">Platelets [#/volume] in Blood</span></td><td><span title="Codes:{http://snomed.info/sct 260371004}">Decreasing</span></td></tr></table></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2 porecotr}">Poor response to corticosteroid treatment</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: Any of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{http://snomed.info/sct 413603009}">Autoimmune hemolytic anemia</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{http://snomed.info/sct 2897005}">Immune thrombocytopenia</span></td></tr></table></blockquote></blockquote></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2 sycasp}">Symptom-causing splenomegaly</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 246120007}">Nodule size</span></td><td>10-?</td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{http://snomed.info/sct 30746006}">Lymphadenopathy</span></td></tr></table></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: All of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 246120007}">Nodule size</span></td><td><span title="Codes:{http://snomed.info/sct 260369004}">Increasing</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://snomed.info/sct 404684003}">Clinical finding (finding)</span></td><td><span title="Codes:{http://snomed.info/sct 30746006}">Lymphadenopathy</span></td></tr></table></blockquote></blockquote></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 26474-7}">Lymphocytes [#/volume] in Blood</span></td><td><span title="Codes:{https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2 ingrfiftyintwomo}">Zunahme mehr als 50 Prozent innerhalb von 2 Monaten, gemessen ab einer absoluten Lymphozytenzahl von mindestens 30.000/µl</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: CLL</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://loinc.org 26474-7}">Lymphocytes [#/volume] in Blood</span></td><td><span title="Codes:{https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2 dopeunsixmo}">Lymphozytenverdopplungszeit unter 6 Monaten, gemessen ab einer absoluten Lymphozytenzahl von mindestens 30.000/µl</span></td></tr></table></blockquote></blockquote></blockquote></blockquote></blockquote></div>
  </text>
  <url
       value="https://www.medizin.uni-greifswald.de/fhir/guideline/cll/EvidenceVariable/PopulationCLLBinetAB"/>
  <name value="PopulationCLLBinetAB"/>
  <title value="Population: CLL und Binet Stadium AB "/>
  <status value="active"/>
  <date value="2025-01-16T09:02:23+00:00"/>
  <description
               value="Population, bei der Binet A oder B sowie eine bestimmte klinische Symptomatik vorliegt"/>
  <actual value="false"/>
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            <coding>
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              <code value="92814006"/>
              <display value="Chronic lymphoid leukaemia, disease"/>
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        <definitionByCombination>
          <code value="any-of"/>
          <characteristic>
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                  <code value="1149099005"/>
                  <display
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                  <version
                           value="http://snomed.info/sct/83821000000107/version/20230412fd"/>
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                  <display
                           value="Clinical stage A chronic lymphocytic leukaemia"/>
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                  <version
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                  <code value="863761000000109"/>
                  <display
                           value="Clinical stage B chronic lymphocytic leukaemia"/>
                </coding>
              </valueCodeableConcept>
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      <characteristic>
        <definitionByCombination>
          <code value="any-of"/>
          <characteristic>
            <linkId value="CLL"/>
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                  <code value="161832001"/>
                  <display value="Weight decreasing"/>
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              <valueCodeableConcept>
                <coding>
                  <system value="http://snomed.info/sct"/>
                  <code value="7520000"/>
                  <display value="Pyrexia of unknown origin"/>
                </coding>
              </valueCodeableConcept>
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          </characteristic>
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            <linkId value="CLL"/>
            <definitionByTypeAndValue>
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              <valueCodeableConcept>
                <coding>
                  <system value="http://snomed.info/sct"/>
                  <code value="42984000"/>
                  <display value="Night sweats"/>
                </coding>
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            <definitionByCombination>
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              <characteristic>
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                    <coding>
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                      <code value="271737000"/>
                      <display value="Anemia"/>
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                  </valueCodeableConcept>
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              </characteristic>
              <characteristic>
                <linkId value="CLL"/>
                <definitionByTypeAndValue>
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              <characteristic>
                <linkId value="CLL"/>
                <definitionByTypeAndValue>
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                    </coding>
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                  <valueCodeableConcept>
                    <coding>
                      <system value="http://snomed.info/sct"/>
                      <code value="302215000"/>
                      <display value="Thrombocytopenic disorder"/>
                    </coding>
                  </valueCodeableConcept>
                </definitionByTypeAndValue>
              </characteristic>
              <characteristic>
                <linkId value="CLL"/>
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                      <code value="260369004"/>
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              </characteristic>
              <characteristic>
                <linkId value="CLL"/>
                <definitionByTypeAndValue>
                  <type>
                    <coding>
                      <system value="http://snomed.info/sct"/>
                      <code value="404684003"/>
                      <display value="Clinical finding (finding)"/>
                    </coding>
                  </type>
                  <valueCodeableConcept>
                    <coding>
                      <system value="http://snomed.info/sct"/>
                      <code value="30746006"/>
                      <display value="Lymphadenopathy"/>
                    </coding>
                  </valueCodeableConcept>
                </definitionByTypeAndValue>
              </characteristic>
            </definitionByCombination>
          </characteristic>
          <characteristic>
            <linkId value="CLL"/>
            <definitionByTypeAndValue>
              <type>
                <coding>
                  <system value="http://loinc.org"/>
                  <code value="26474-7"/>
                  <display value="Lymphocytes [#/volume] in Blood"/>
                </coding>
              </type>
              <valueCodeableConcept>
                <coding>
                  <system
                          value="https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2"/>
                  <code value="ingrfiftyintwomo"/>
                  <display
                           value="Zunahme mehr als 50 Prozent innerhalb von 2 Monaten, gemessen ab einer absoluten Lymphozytenzahl von mindestens 30.000/µl"/>
                </coding>
              </valueCodeableConcept>
            </definitionByTypeAndValue>
          </characteristic>
          <characteristic>
            <linkId value="CLL"/>
            <definitionByTypeAndValue>
              <type>
                <coding>
                  <system value="http://loinc.org"/>
                  <code value="26474-7"/>
                  <display value="Lymphocytes [#/volume] in Blood"/>
                </coding>
              </type>
              <valueCodeableConcept>
                <coding>
                  <system
                          value="https://www.medizin.uni-greifswald.de/fhir/guideline/cll/CodeSystem/cll-v2"/>
                  <code value="dopeunsixmo"/>
                  <display
                           value="Lymphozytenverdopplungszeit unter 6 Monaten, gemessen ab einer absoluten Lymphozytenzahl von mindestens 30.000/µl"/>
                </coding>
              </valueCodeableConcept>
            </definitionByTypeAndValue>
          </characteristic>
        </definitionByCombination>
      </characteristic>
    </definitionByCombination>
  </characteristic>
</EvidenceVariable>